Start with the enclosure
Check the basics for Tliltocatl vagans: fresh water, suitable moisture, a secure retreat, good ventilation and a practical temperature range of 20–26°C. A clear husbandry problem matters more than a single evening of unusual activity.
For Mexican Red Rumps, keep a water dish available and maintain a modest moisture gradient; avoid persistently wet substrate. If the enclosure is obviously too wet, too dry or difficult for the spider to use normally, correct that issue before looking for a more complicated explanation.
Know what is normal
For Tliltocatl vagans, Mexican Red Rumps are terrestrial tarantulas, so normal retreat use should make sense for that lifestyle. A hidden spider is not automatically a stressed spider, and a visible one is not automatically comfortable.
With Tliltocatl vagans, changes from the individual's usual routine are more informative than a generic list of 'stress signs'. Compare activity, feeding and retreat use with what the same spider normally does.
Climbing, pacing and restlessness
If a Mexican Red Rump repeatedly climbs or paces, check enclosure shape, moisture and recent disturbance. Mature males of Tliltocatl vagans may also roam much more after the ultimate moult.
One short burst of activity from Tliltocatl vagans matters less than a persistent pattern combined with poor body condition or an obvious enclosure problem.
Feeding changes
With Tliltocatl vagans, food refusal in Mexican Red Rumps is often normal around premoult, after a heavy meal or following a rehouse. Keep water available and remove ignored live prey.
If Tliltocatl vagans stops eating but remains well hydrated and otherwise behaves normally, observation is usually more useful than repeatedly opening the enclosure and offering food.
Changes that need quicker attention
In Tliltocatl vagans, visible injury, haemolymph loss, severe dehydration, inability to stand normally or major loss of coordination in a Mexican Red Rump deserves prompt attention.
If Tliltocatl vagans is physically deteriorating, correct any obvious husbandry problem immediately and seek experienced or veterinary help where appropriate.